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Major characteristics
  • Growth retardation (below 3rd % on growth charts)                 
    • The average adult height of males is ~4 feet 11 inches (151.2 cm) and that of females is 4 feet 7 inches (139.9 cm.)
    • Growth is typically proportionate       
    • However, most individuals with RSS have a short arm span.
    • Slow growth in utero is an essential feature of RSS.
  • Limb, body, and facial asymmetry may be present
    • Limb length asymmetry most common
    • Children may have different foot sizes
  • Characteristic facial features
    • Triangular shaped face
    • Prominent forehead
    • Small, narrow chin
  • Motor, speech, and/or cognitive delays
Other findings
  • Hypoglycemia (low blood sugar)
    • Children with RSS have little subcutaneous fat, are quite thin, and often have poor appetites.
    • They are at risk for hypoglycemia with any prolonged fast, including surgery.
    • Excessive sweating is often associated with hypoglycemia
  • Gastrointestinal findings
    • Reflux
    • Food aversions
    • Constipation
  • Skin pigment changes
    • Including cafĂ© au lait spots
  • Kidney problems
  • Teeth crowding
    • Important to have good oral hygiene
  • Fingers and toes
    • 5th finger curved
    • Short, stubby fingers and toes